The test can only be performed on Tuesdays and Thursdays due to the need for rapid transport to the laboratory performing the test.
The lymphocyte transformation test is used in dentistry in the detecting hypersensitivity to root canal filling materials root canals (composites, cements and others) and in patients using dentures and having implants placed. Metals that cause a reaction hypersensitivity include beryllium, nickel, cobalt, chromium, tantalum and vanadium, as well as as well as titanium previously considered a non-allergenic metal.