Antibodies against SRP

Antibodies against signal recognition particles (SRPs) are found in patients with polymyositis. Their presence predisposes to myocardial changes, significant weakness in muscle strength muscle and poor response to treatment. The detection of these antibodies worsens the patient's prognosis. Polymyositis usually begins slowly. A progressive muscle weakness, especially in the arms, legs and neck and back It is difficult to change body position, walk up stairs, speaking, swallowing and also breathing.