Antibodies against Schistosoma spp. IgG (Western blot)

Determination of IgG antibodies against Schistosoma mansoni is performed in the diagnosis of schistosomiasis.

Schistosoma is a parasitic disease caused by flukes of the genus Schistosoma, which includes Schistosoma mansoni - or venous fluke, a species found in Africa, North America and also on the Arabian Peninsula.
Human infection occurs through bathing in larvae-contaminated water. Penetrating the skin, the larvae enter the circulation and, along with the blood move to various organs of the body. There they mature and copulate, then migrate to the intestine and there lay eggs. The eggs of the fluke through the urinary or digestive system can get out of the body or through the circulatory system enter to various organs and there induce inflammation, as a result of which as a result of which damage can occur to the organ in which they are located they are located. Parasite eggs can reach the skin, brain, muscles, adrenal glands, eyes, urinary bladder. They can also penetrate into the uterus, fallopian tubes, and ovaries. Adult parasites reside in the lumen of the vessels supplying the intestines, liver or bladder, among others urinary bladder.
Determination of IgG antibodies against schistosome is a non-invasive test that can diagnose infection even before the proliferation of the fluke occurs. The assay performed to to confirm a positive IgG antibody result p/Schistosoma.