Campylobacter jejuni IgA antibodies

Campylobacter jejuni is a gram negative bacterium that is considered the the main etiological agent of human diarrhea worldwide world.
It causes gastroenteritis and sepsis known as campylobacteriosis. Infections with these microorganisms are caused mainly the consumption of food products contaminated with bacteria of animal origin, primarily improperly prepared poultry meat.
There are also known cases of human infection following direct contact with domestic or livestock.
Most infections are observed among children under 6 years of age and adults between the ages of 25 and 30 years.
Determination of the level of specific antibodies in a serum sample, should be be considered as a complementary test to bacteriological diagnostics and/or genetic (detection of bacterial DNA). In the course of infection caused by Campylobacter bacilli, serum antibodies are produced IgA, IgM and IgG class antibodies.
Class IgA antibodies to C. jejuni bacilli antigens appear appear in serum around the fifth day after infection reaching maximum levels in the second week of illness.
They can be detected up to three months after the onset of clinical symptoms To confirm an acute intestinal infection, the highest diagnostic value diagnostic value is the demonstration of a significant increase in the level of antibodies in two serum samples obtained 2 weeks apart.

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