Onconeuronal antibodies p/Ma-2/Ta (IB)

Onconeuronal antibodies are antibodies that attack and destroy the nervous system. Determinations of onconeuronal antibodies allow, with an appropriate clinical picture, to make a confident diagnosis of neurological paraneoplastic syndrome and taking diagnostic measures aimed at determining the localization of the primary tumor and implementation of specific treatment. Each of the antibodies is specific to a particular paraneoplastic syndrome and cancer. Anti-Ma-2 antibodies are characteristic of limbic encephalitis, inflammation of the brainstem, cerebellar degeneration. They can accompany such cancers such as testicular cancer, lung cancer and breast cancer.