Nifedipine

Nifedipine is a first-generation calcium channel blocker drug By reducing the entry of calcium ions into the smooth muscle cells of the coronary, peripheral and cutaneous vessels, as well as the heart muscle causes peripheral vasodilation. As a consequence, it leads to this leads to a reduction in peripheral resistance and blood pressure. The drug The drug additionally reduces platelet aggregation and prevents the formation of atherosclerotic plaques. Indications for use include migraine, chronic stable coronary artery disease, hypertension arterial hypertension, hypertrophic cardiomyopathy, and esophageal achalasia Determination of nifedipine concentration is helpful in monitoring the dosage of the drug and in case of suspected overdose or poisoning.