CK-MB activity

Creatine kinase (CK) is an enzyme that catalyzes the phosphorylation of creatine. It is found mainly in skeletal muscle fibers, cardiomyocytes and in the brain.

Cytoplasmic CK exists in the form of 3 isoenzymes, which are dimers composed of the M (muscle) and B (brain) subunits: CK-MM, CK-MB, CK-BB. The parameter complements the diagnosis of fresh myocardial infarction myocardium.

Increased concentration of CK-MB also occurs in:

• first-diastole ventricular, 
• inflammation of the myocardium cardiac muscle, 
• acute heart failure heart, 
• heart trauma, 
• pulmonary embolism,
• drug use cardiotoxic drugs,