Eosinophil cationic protein ECP

Determination of eosinophil cationic protein (ECP) levels in serum is useful in diagnosing allergic inflammatory reactions inflammatory reactions and controlling their activity, as well as assessing the use of appropriate anti-inflammatory treatment. ECP is regarded as a marker of eosinophil activation in various disease states Determination of serum ECP levels is performed in the diagnosis of allergology, especially in monitoring asthma and the effects of specific immunotherapy. An increase in the concentration of this protein in the blood occurs in exacerbations of atopic diseases and shows a positive correlation with the severity of allergic inflammation. High ECP concentration is also found in the initial phase of myocardial infarction with eosinopenia. In ankylosing spondylitis serum ECP is considered a marker of inflammation.