ALEX3 - Comprehensive Allergy Test for 300 Allergens

The ALEX³ panel is an advanced IgE-dependent allergy test that provides significantly more precise information than classic tests. Currently, ALEX³ is the most comprehensive allergy test available on the market. It analyzes a total of 300 allergens, of which as many as 107 allergens are available diagnostically exclusively in this panel.

How to prepare for the test?

• You can come for the test at a convenient time for you, regardless of the time of day.
• You don't need to be fasting, but don't eat heavy meals just before blood collection.
• ALEX3 allergy diagnostics is a test that can be performed on patients of all ages – from infants, usually from 6 months of age – to the elderly.
• You don't need to discontinue your medications, including antihistamines or steroids.

What is the ALEX3 test?

The ALEX3 test is the most comprehensive panel currently available in allergy diagnostics, allowing for a very accurate assessment of the most common allergies in both adults and children. Among the 300 allergens analyzed in the test, there are 121 inhalant allergens, 162 food allergens, and 17 other allergens.

Inhalant allergens

The panel includes the most important allergens present in the air and everyday environment, including:

• pollen from trees, grasses, and weeds of greatest clinical significance,
• house dust mites, including Dermatophagoides pteronyssinus and Dermatophagoides farinae,
• animal allergens, including fur and dander from cats, dogs, horses, rabbits, hamsters, and guinea pigs,
• molds and yeasts most commonly causing allergy symptoms, present both indoors and outdoors, including Alternaria alternata, Aspergillus fumigatus, Cladosporium herbarum, Malassezia sympodialis, Penicillium chrysogenum.

Food allergens

The test enables detailed assessment of diet-related allergies, including allergies to:

• nuts, including those less commonly included in standard tests, such as pistachio or Brazil nut,
• legumes, including: soy, lentils, peas, and chickpeas,
• fish and seafood: numerous fish species, including carp, cod, salmon, tuna, Atlantic mackerel, herring, as well as crustaceans and mollusks,
• eggs and milk,
• grains and seeds, such as wheat and barley,
• fruits and vegetables, including those most commonly responsible for cross-allergies.

Other allergens

ALEX3 also detects allergies to:

• insect venom,
• latex,
• alpha-gal,
• European pigeon tick.
• and others.

Compared to the previous version of the test (ALEX²), the panel has been expanded not only with additional allergens, but primarily with new protein families and quality control mechanisms that significantly impact diagnostic accuracy. The key advantage of ALEX³ is the ability to more accurately distinguish what the body reacts to primarily versus what is merely a cross-reaction.

Modern technologies – precise diagnostics

Particularly noteworthy is the use of a modern CCD blocker with 98% effectiveness. Its purpose is to eliminate false-positive results. An element that increases the reliability of the test is Sample Pipetting Control (SPC) – a built-in quality control mechanism that minimizes the risk of pre-analytical errors, e.g., it analyzes whether the appropriate sample volume was collected.

How is the test performed?

The test involves collecting a small amount of venous blood by qualified personnel at a Collection Point.

ALEX3 allergy diagnostics – how to interpret the test result?

A positive result means that the body reacts with an allergy to a given allergen.

The ALEX³ panel is a good choice for patients who want to obtain accurate information necessary to make a decision about specific immunotherapy (desensitization) or to plan individualized therapeutic recommendations, including dietary ones.

The results obtained should always be discussed with an allergist – combined with medical history and symptoms, it allows for a complete diagnosis.