Plasma heparin activity (anti-Xa)

Low-molecular-weight heparins are derived from heparins unfractionated. More than a dozen preparations of low-molecular-weight heparins. Heparins Low molecular weight, compared to unfractionated heparin, show significantly reduced antithrombin activity (anti - IIa), and their anticoagulant activity is mainly based on inhibition of factor Xa (active) activity. Heparins low-molecular-weight heparins are administered subcutaneously and are used in, among other things primary prophylaxis of venous thromboembolism, treatment of deep vein thrombosis, pulmonary embolism, unstable coronary artery disease, and in interventional cardiology Control of the effectiveness of low-molecular-weight heparins should be carried out in patients with renal failure, in people who are obese, children and pregnant women. To assess their effect measurement of anti-Xa activity is used.