11-deoxycortisol

11-deoxycortisol is an adrenal steroid formed by the action of progesterone 21-hydroxylase due to the action of 21-hydroxylase on progesterone.

The assay is used to diagnose congenital adrenal hyperplasia - a a genetic defect involving a genetic mutation that results in the which results in the elimination of one of the key enzymes involved in the synthesis of adrenal hormones.